Top Hotels Near Duke Medical Center

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Nestled in the very heart of the vibrant city, Duke Medical Center stands as a beacon of excellence in healthcare and innovation, attracting visitors from across the globe for both medical and academic pursuits. The need for comfortable, convenient accommodation is paramount for those coming to the Center, whether for medical appointments, visiting loved ones, or engaging in collaborative projects. This has led to a growing demand for quality hotels in the vicinity, offering rest and relaxation a stone's throw away from the medical Center.

Recognizing the importance of finding the perfect stay, our guide to the best hotels near Duke Medical Center is crafted with care, ensuring every recommendation meets the highest standards of comfort, convenience, and customer service. Each hotel on our list has been selected for its proximity to the Center, ensuring easy commutes and peace of mind during your stay. Furthermore, we've considered the diverse needs of visitors, from families requiring spacious accommodations to business travelers seeking high-speed internet and workspaces.

Beyond the primary necessity of proximity to Duke Medical Center, our insights delve into the added benefits these hotels offer, such as complimentary shuttle services to the medical Center, on-site dining options, and fitness facilities to help guests unwind. Our article is designed to simplify your planning process, allowing you to focus on what matters most during your visit. With a comprehensive overview of the top hotels near Duke Medical Center, finding your ideal accommodation has never been easier, ensuring a comfortable and stress-free stay amidst the bustling city life.

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Our Top 6

(Sorted by rating & number of reviews)

1. Sleep Inn & Suites Center
2. Holiday Inn Express Hotel & Suites Center, An Ihg Hotel
3. Americas Best Value Inn Center
4. Best Western Plus Classic Inn And Suites
5. Hampton Inn & Suites Center
6. Super 8 By Wyndham Center Motel

Comfort and Convenience: Top Hotels Near Major Medical Centers

Check Availability

Center
Jan 28, 2026 - Jan 29, 2026

Sleep Inn & Suites Center

7.8

Good

(60 Reviews)

+ 71 photos
Sleep Inn & Suites Center offers a welcoming environment for those looking for value accommodation near medical facilities. This hotel stands out for its blend of affordability and comfort, providing guests with a range of amenities including free Wi-Fi, a fitness Center, and an indoor pool. The complimentary hot breakfast is a perfect start to a day of appointments. Located conveniently near local medical centers, Sleep Inn & Suites ensures guests have an easy commute. The attentive staff and clean, comfortable rooms make it an excellent choice for those prioritizing both budget and quality during their stay.
Address: 181 Civic Center
Rating: Good 7.8 (60 Reviews)
Rooms: 55
Price: From 88$

Holiday Inn Express Hotel & Suites Center, An Ihg Hotel

8.7

Good

(53 Reviews)

+ 68 photos
Perfectly blending comfort with convenience, the Holiday Inn Express Hotel & Suites Center is a top choice for those visiting nearby medical centers. This hotel is renowned for its welcoming atmosphere, modern accommodations, and top-tier services, including a complimentary breakfast buffet to start your day right. Guests can take advantage of the free high-speed internet, on-site fitness Center, and an indoor pool for relaxation. Situated just a short drive from major medical facilities, it offers the perfect base for medical visits, ensuring minimal commute time. The hotel's commitment to guest satisfaction is evident in its spacious rooms, equipped with comfortable bedding and a dedicated work area, making it an ideal choice for both short and long-term stays.
Address: 143 Express Blvd
Rating: Good 8.7 (53 Reviews)
Rooms: 60
Price: From 138$

Budget-Friendly Accommodations: Value Hotels Near Medical Facilities

Finding budget-friendly accommodations doesn't mean you have to compromise on quality or location when visiting medical centers. This section is dedicated to those who prioritize affordability while also seeking decent proximity to medical facilities. Each hotel chosen offers competitive rates, essential amenities, and the peace of mind knowing you're not far from where you need to be. These picks ensure that economical choices are still comfortable, convenient, and capable of providing a pleasant stay.

Americas Best Value Inn Center

6.9

Good

(60 Reviews)

+ 85 photos
For those seeking practical accommodations without sacrificing quality, the Americas Best Value Inn Center offers a compelling choice. This hotel prides itself on offering excellent value, combining affordable rates with amenities designed for guest comfort and convenience. Located conveniently near major medical centers, it ensures easy access to medical appointments and the peace of mind that comes with being close by. The rooms are tastefully furnished, providing a cozy retreat with all the necessities, including complimentary Wi-Fi, cable TV, and a continental breakfast. The staff's attention to detail and willingness to accommodate the needs of guests visiting medical centers make it a standout choice. Whether you're in town for medical reasons or simply exploring the area, Americas Best Value Inn Center provides a welcoming and budget-friendly base for your stay.
Address: 1005 Hurst Street
Rating: Good 6.9 (60 Reviews)
Rooms: 50
Price: From 52$

Best Western Plus Classic Inn And Suites

7.6

Good

(99 Reviews)

+ 66 photos
For visitors who seek a balance between affordability and comfort, the Best Western Plus Classic Inn and Suites is a prime choice near medical centers. This hotel is praised for its competitive pricing, coupled with a range of amenities designed for a relaxing stay. Guests can enjoy a complimentary breakfast, an outdoor pool, and a modern fitness Center. The spacious rooms, equipped with microwaves and refrigerators, offer the convenience of home comforts. Its proximity to medical facilities means less travel stress, while the friendly staff go above and beyond to cater to the needs of guests visiting for medical reasons.
Address: 210 Moffett Drive
Rating: Good 7.6 (99 Reviews)
Rooms: 60
Price: From 58$

Hampton Inn & Suites Center

7.9

Good

(49 Reviews)

+ 37 photos
The Hampton Inn & Suites Center stands out for its proximity to medical centers, offering visitors a harmonious blend of comfort and convenience. From the moment you enter, you're greeted with warm hospitality and a commitment to excellence that the Hampton brand is known for. The hotel features a variety of room types to suit any traveler's needs, each equipped with comfortable beds, free Wi-Fi, and a convenient work desk. Guests can enjoy a complimentary hot breakfast each morning, an outdoor pool, and a fitness Center to stay active. Its location makes it incredibly convenient for medical Center visitors, providing a hassle-free experience to and from appointments. The Hampton Inn & Suites is more than just a place to stay; it's a haven of relaxation, ensuring you're well-rested and ready for the day ahead.
Address: 141 Express Boulevard
Rating: Good 7.9 (49 Reviews)
Rooms: 66
Price: From 149$

Super 8 By Wyndham Center Motel

7.2

Good

(71 Reviews)

+ 45 photos
Super 8 by Wyndham Center offers an economical stay without sacrificing the conveniences necessary for those visiting nearby medical facilities. This hotel is known for its clean, comfortable rooms and friendly service, ensuring a pleasant stay for all guests. Amenities include free Wi-Fi, continental breakfast, and in-room coffee makers, adding value to your stay. Its location provides easy access to local medical centers, making it an ideal choice for guests attending to medical needs. Super 8 balances affordability with a commitment to service and comfort, making it a smart choice for budget-conscious travelers.
Address: 907 Hurst St
Rating: Good 7.2 (71 Reviews)
Rooms: 40
Price: From 81$